distempers

verb

1. To temper or mix unduly; to make disproportionate; to change the due proportions of.
2. To derange the functions of, whether bodily, mental, or spiritual; to disorder; to disease.
3. To deprive of temper or moderation; to disturb; to ruffle; to make disaffected, ill-humoured, or malignant.
4. To intoxicate.