breakthrough

/ˈbɹeɪk.θɹuː/ · adj

Meaning

Characterized by major progress or overcoming some obstacle.
Involving the contraction of a disease by a person with a decreased susceptibility, such as a person who has been vaccinated to help prevent that disease.
An advance through and past enemy lines.
Any major progress; such as a great innovation or discovery that overcomes a significant obstacle.
The penetration of the opposition's defence.
The penetration of a separating wall or the remaining distance to an adjacent hollow (a crosscut in mining) or between two parts of a tunnel build from both ends.
The emergence or one or more symptoms of a condition despite medication or other medical treatment.

From break + through. Compare German Durchbruch and Dutch doorbraak (“breakthrough”, literally “through-break”).

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